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甘油三酯葡萄糖指数与慢性肾脏病相关性的研究进展
杜莹莹1，伍秋霞2，梁美媛1，唐　盛2，邓梅秋2
1.右江民族医学院，百色 533000；2.广西壮族自治区人民医院（广西医学科学院），南宁 530021
摘要:
［摘要］　慢性肾脏病（CKD）发病率呈逐年上升趋势，已成为全球性的公共卫生问题，优化CKD管理策略，提高防治水平，对控制CKD的发生和发展，减少终末期肾衰竭的发生至关重要。近年来，代谢紊乱与CKD的相关性研究已成为肾脏病防治领域的重点关注方向。胰岛素抵抗（IR）是CKD发生和发展的关键因素之一，甘油三酯葡萄糖（TyG）指数在临床中易于获取，可作为IR替代生物标志物，同时可作为预测CKD的潜在生物标志物，逐渐受到重视。该文对TyG指数与CKD相关性的研究进展作一综述。
关键词:  甘油三酯葡萄糖指数  慢性肾脏病  防治  胰岛素抵抗  代谢综合征
DOI：10.3969/j.issn.1674-3806.2025.03.21
分类号:R 692
基金项目:广西科技计划项目（编号:桂科AB24010065）
Research progress on the correlation between triglyceride-glucose index and chronic kidney disease
DU Yingying1, WU Qiuxia2, LIANG Meiyuan1, TANG Sheng2, DENG Meiqiu2
1.Youjiang Medical University for Nationalities, Baise 533000, China; 2.The People′s Hospital of Guangxi Zhuang Autonomous Region(Guangxi Academy of Medical Sciences), Nanning 530021, China
Abstract:
［Abstract］　The incidence of chronic kidney disease(CKD) is increasing year by year and CKD has become a global public health problem. Optimizing the management strategy of CKD and improving the prevention and treatment level of CKD are crucial for controlling the occurrence and development of CKD and reducing the occurrence of end-stage renal failure. In recent years, studies on the correlation between metabolic disorders and CKD have become the focus of attention in the field of prevention and treatment of kidney diseases. Insulin resistance(IR) is one of the key factors in the occurrence and development of CKD, and triglyceride-glucose(TyG) index is easy to obtain in clinical practice, and can be used as an alternative biomarker of IR and a potential biomarker for predicting CKD. Therefore, TyG index has gradually attracted attention. In this paper, the research progress on the correlation between TyG index and CKD is reviewed.
Key words:  Triglyceride-glucose(TyG) index  Chronic kidney disease(CKD)  Prevention and treatment  Insulin resistance(IR)  Metabolic syndrome(MS)