| 摘要: |
| ［摘要］ 目的 分析4种中国女性常用更年期量表间的相关性和一致性。方法 回顾性分析2016年1月至2024年12月就诊于中国多个地区27家医院的13 498例更年期女性的电子问卷数据，问卷包括了改良Kupperman评分（mKI）、绝经特异生存质量量表（MENQOL）、医院焦虑和抑郁量表（HADS）、匹兹堡睡眠质量指数（PSQI），比较上述4种量表用于评估更年期相关症状的相关性和一致性。其中MENQOL包含血管舒缩症状、心理社会状态、生理状态、性生活4个领域；HADS分为焦虑量表（HADS-A）和抑郁量表（HADS-D）。结果 研究对象中位年龄为52岁，mKI总分与MENQOL各领域得分呈中至强相关（rs分别为0.659、0.632、0.686、0.512），判断症状有无的一致性中等（Kappa分别为0.350、0.330、0.217、0.283），P均<0.001。mKI与HADS子量表呈弱至中等相关（rs分别为0.531、0.363），MENQOL心理社会状态得分与HADS子量表呈中至强相关（rs分别为0.665、0.479），P均<0.01，评价结果一致性较差（mKI与HADS子量表的Kappa分别为0.094、0.083；MENQOL心理社会状态与HADS子量表的Kappa分别为0.053、0.041，P均<0.001）。mKI总分和MENQOL生理状态得分与PSQI得分呈强相关（rs分别为0.634、0.593，P<0.01），mKI总分与PSQI评价结果一致性中等（Kappa=0.306，P<0.01），MENQOL生理状态与PSQI评价结果一致性较差（Kappa=0.074，P<0.001）。结论 临床应视具体情况选用和组合适当的问卷，mKI和MENQOL相关性较强；情绪困扰严重的患者，可考虑进行HADS评估。 |
| 关键词: 绝经 更年期综合征 围绝经期评定量表 量表临床应用 |
| DOI：10.3969/j.issn.1674-3806.2025.05.07 |
| 分类号:R 711.75 |
| 基金项目:北京协和医院中央高水平医院临床科研专项项目（编号：2022-PUMCH-B-123）；国家重点研发计划课题（编号：2022YFC2703802）；北京协和医院人才培育支持计划项目（编号：UHB12388）；国家自然科学基金项目（编号：82201781）；国家临床重点专科建设项目（编号：U114000） |
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| Correlation analysis of common menopause rating scales for Chinese women |
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YANG Lingjin, TANG Ruiyi, CHEN Rong
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Gynecological Endocrinology and Reproduction Center, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Clinical Research Center for Obstetric and Gynecologic Diseases, National Center for Healthcare Quality Management in Gynecological Diseases, Beijing 100730, China
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| Abstract: |
| ［Abstract］ Objective To analyze the correlation and consistency among 4 commonly used menopause scales for Chinese women. Methods The electronic questionnaire data of 13 498 menopausal women who visited their doctors in 27 hospitals in multiple regions of China from January 2016 to December 2024 were retrospectively analyzed. The questionnaires included modified Kupperman Index(mKI), Menopause-Specific Quality of Life Questionnaire(MENQOL), Hospital Anxiety and Depression Scale(HADS) and Pittsburgh Sleep Quality Index(PSQI). The correlation and consistency among the above 4 scales in evaluating menopausal-related symptoms were compared. The MENQOL encompassed 4 dimensions: vasomotor symptoms, psychosocial state, physiological state and sexual life. The HADS consisted of Hospital Anxiety and Depression Scale-Anxiety(HADS-A) and Hospital Anxiety and Depression Scale-Depression(HADS-D). Results The median age of the research subjects was 52 years. The total scores of mKI were moderately to strongly correlated with the scores of each dimension of MENQOL(The values of rs were 0.659, 0.632, 0.686 and 0.512, respectively). The consistency in judging the presence or absence of symptoms was moderate(The values of Kappa were 0.350, 0.330, 0.217 and 0.283, respectively), and the differences were statistically significant(P<0.001). The mKI had a weak to moderate correlation with HADS subscales(The values of rs were 0.531 and 0.363, respectively). The scores of psychosocial state in MENQOL had a moderate to strong correlation with HADS subscales(The values of rs were 0.665 and 0.479, respectively)(P<0.01). The consistency of the evaluation results was poor(The Kappa values of mKI and HADS subscales were 0.094 and 0.083, respectively, and the Kappa values of psychosocial state in MENQOL and HADS subscales were 0.053 and 0.041, respectively, P<0.001). The total scores of mKI and the scores of physiological state in MENQOL were strongly correlated with the scores of PSQI(The values of rs were 0.634 and 0.593, respectively, P<0.01). The consistency of the evaluation results between the total scores of mKI and the scores of PSQI was moderate(Kappa=0.306, P<0.01). The consistency of the evaluation results between the scores of physiological state in MENQOL and the scores of PSQI was poor(Kappa=0.074, P<0.001). Conclusion Appropriate questionnaires should be selected and combined according to specific circumstances in clinical practice. The correlation between mKI and MENQOL is relatively strong. Patients with severe emotional distress may consider undergoing HADS evaluation. |
| Key words: Menopause Menopausal syndrome Perimenopausal rating scales Clinical application of rating scales |
