| 摘要: |
| ［摘要］ 目的 分析FOCUS计划对急性白血病（AL）患者及其家庭主要照顾者应对方式、家庭韧性和生活质量的影响。方法 招募2023年7月至12月空军军医大学唐都医院收治的64例AL患者及其家庭主要照顾者为研究对象，采用随机数字表法将患者及其家庭主要照顾者分为干预组和对照组，各32例。对照组行常规护理+随访，干预组行常规护理+FOCUS计划+随访，干预时间为12周。分别于干预前（T0）、干预4周后（T1）、干预12周后（T2）对患者及其家庭主要照顾者进行问卷调查。比较干预前后两组患者及其家庭主要照顾者应对方式、家庭韧性和生活质量的变化情况。结果 干预组中病情恶化2例，主动退出1例，失访2例，最终纳入27例；对照组中主动退出2例，失访4例，最终纳入26例。干预组患者T1、T2时间点家庭坚韧性量表（FHI）评分和特质应对问卷（TCSQ）中积极应对评分高于T0时间点，消极应对评分低于T0时间点，差异有统计学意义（P<0.05）。T1、T2时间点干预组患者白血病特异性生活质量量表（FACT-Leu）评分、FHI评分高于对照组，消极应对评分低于对照组，差异有统计学意义（P<0.05）。干预组家庭主要照顾者T1、T2时间点FHI评分、TCSQ中积极应对评分高于T0时间点，消极应对评分低于T0时间点，对照组家庭主要照顾者T1、T2时间点FHI评分高于T0时间点，差异有统计学意义（P<0.05）。T1、T2时间点干预组家庭主要照顾者简明生活质量量表（SF-12）评分、FHI评分以及TCSQ中积极应对评分高于对照组，消极应对评分低于对照组，差异有统计学意义（P<0.05）。结论 FOCUS计划可有效促进AL患者及其家庭主要照顾者的积极应对，减少消极应对，同时增强家庭韧性，提高生活质量。 |
| 关键词: 急性白血病 家庭主要照顾者 应对方式 家庭韧性 生活质量 |
| DOI：10.3969/j.issn.1674-3806.2025.08.19 |
| 分类号:R 473.5 |
| 基金项目:空军军医大学“快速响应”科研课题（编号：2023KXKT062） |
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| Effects of FOCUS program on coping styles, family resilience and quality of life in acute leukemia patients and their primary family caregivers |
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MU Hezi1,2, LIU Qin1, CUI Yi1, CHEN Changchang1, ZHANG Yinling1
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1.Department of Nursing, Air Force Medical University, Xi′an 710032, China; 2. Department of Orthopedics, Tangdu Hospital, Air Force Medical University, Xi′an 710038, China
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| Abstract: |
| ［Abstract］ Objective To analyze the effects of FOCUS［family involvement(F), optimistic attitude(O), coping effectiveness(C), uncertainty reduction(U) and symptom management(S)］ program on coping styles, family resilience and quality of life in acute leukemia(AL) patients and their primary family caregivers. Methods Sixty-four patients with AL who were admitted to Tangdu Hospital, Air Force Medical University from July 2023 to December 2023 and their primary family caregivers were recruited as research subjects. The patients and their primary family caregivers were divided into intervention group and control group by using random number table method, with 32 cases in each group. The control group received routine care+follow-up, while the intervention group received routine care+FOCUS program+follow-up. The intervention period was 12 weeks. Questionnaires were conducted on the patients and their primary family caregivers respectively before intervention(T0), 4 weeks after intervention(T1), and 12 weeks after intervention(T2). The changes in coping styles, family resilience, and quality of life in the AL patients and their primary family caregivers were compared between the two groups before and after intervention. Results In the intervention group, 2 patients had deteriorated conditions, and 1 patient withdrew voluntarily, and 2 patients were lost to follow-up, and finally 27 patients were included. In the control group, 2 patients withdrew voluntarily, and 4 patients were lost to follow-up, and finally 26 patients were included. In the patients of the intervention group, Family Hardiness Index(FHI) scale scores and the positive coping scores in Trait Coping Style Questionnaire(TCSQ) at T1 and T2 time points were higher than those at T0 time point, and the negative coping score in TCSQ at T1 and T2 time points were lower than those at T0 time point, and the differences were statistically significant(P<0.05). The Functional Assessment of Cancer Therapy—Leukemia(FACT-Leu) scale scores and FHI scores at T1 and T2 time points in the patients of the intervention group were higher than those in the patients of the control group, while the negative coping score in TCSQ at T1 and T2 time points in the patients of the intervention group were lower than those in the patients of the control group, with statistically significant differences between the two groups(P<0.05). In the primary family caregivers of the intervention group, FHI scale scores and the positive coping scores in TCSQ at T1 and T2 time points were higher than those at T0 time point, and the negative coping scores in TCSQ at T1 and T2 time points were lower than those at T0 time point and in the primary family caregivers of the control group, FHI scale scores at T1 and T2 time points were higher than those at T0 time point, and the differences were statistically significant(P<0.05). The 12-Item Short-Form(SF-12) scores, FHI scores, and the positive coping scores in TCSQ at T1 and T2 time points in the primary family caregivers of the intervention group were higher than those in the primary family caregivers of the control group, while the negative coping scores in TCSQ at T1 and T2 time points in the primary family caregivers of the intervention group were lower than those in the primary family caregivers of the control group, with statistically significant differences between the two groups(P<0.05). Conclusion The FOCUS program can effectively promote positive coping responses, reduce negative coping responses, enhance family resilience, and improve quality of life in both AL patients and their primary family caregivers. |
| Key words: Acute leukemia(AL) Primary family caregiver Coping styles Family resilience Quality of life |
