| 摘要: |
| [摘要] 晚期甲状腺癌因传统治疗效果有限,仍是临床难题。分子靶向治疗虽然可延长患者无进展生存期,但是耐药问题限制了其长期疗效;免疫治疗与靶向或放射性碘联合应用展现出协同潜力,然而整体疗效仍需进一步优化。该文对晚期甲状腺癌精准医疗的研究进展作一综述。 |
| 关键词: 晚期甲状腺癌 精准医疗 分子靶向治疗 免疫治疗 |
| DOI:10.3969/j.issn.1674-3806.2026.01.19 |
| 分类号:R 736 |
| 基金项目:新疆维吾尔自治区自然科学基金资助项目(编号:2021D01C325) |
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| Research progress in precision medicine for advanced thyroid cancer |
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DENG Chao, WUFUER Yimaer
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Department of Blood Vessel and Thyroid Surgery, the First Teaching Hospital of Xinjiang Medical University, Urumqi 830054, China
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| Abstract: |
| [Abstract] Advanced thyroid cancer remains a clinical challenge due to the limited effectiveness of traditional treatments. Although molecular targeted therapy can prolong the progression-free survival of the patients, the problem of drug resistance limits its long-term effectiveness. The combination of immunotherapy with targeted therapy or radioiodine shows potential for synergy, but the overall efficacy still needs further optimization. In this paper, the research progress in precision medicine for advanced thyroid cancer is reviewed. |
| Key words: Advanced thyroid cancer Precision medicine Molecular targeted therapy Immunotherapy |