| 摘要: |
| ［摘要］ 目的 比较分析变应性鼻炎患者不同产地屋尘螨变应原在变应性鼻炎的皮试结果。方法 306例中重度持续性变应性鼻炎患者，随机分组进行国产屋尘螨变应原皮内试验或国际标准阿罗格屋尘螨变应原皮肤点刺试验。结果 国产屋尘螨变应原皮内试验阳性率88.69%(137/154)，阿罗格屋尘螨变应原点刺法试验阳性率90.79%(138/152)，两者间差异无统计学意义(P>0.05)；国产屋尘螨变应原IDT阳性达(++)及以上为62.34%(96/154)，阿罗格屋尘螨变应原SPT阳性达(++)及以上为84.87%(129/152)，两者间差异有统计学意义(P<0.001)。无严重不良反应发生。结论 国产屋尘螨变应原和阿罗格屋尘螨变应原均具有较高的阳性率，阿罗格屋尘螨变应原点刺法试验具有更高的灵敏性及特异性。 |
| 关键词: 变应原 变应性鼻炎 皮内试验 皮肤点刺实验 |
| DOI： |
| 分类号:R 765.21 |
| 基金项目: |
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| Comparative analysis on the skin allergen tests among cases with allergic rhinitis with dermatophagoides pteronyssinus allergen |
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LU Qiu-tian, LIANG Jian-ping, HE Ning, et al.
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Department of Otolaryngology, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To analyze the skin allergen test in a comparative way among cases with allergic rhinitis(AR) tested with Dermatophagoides pteronyssinus(Der p) allergen.Methods Three hundred and six cases with moderate to severe AR underwnet intradermal test (IDT) or skin prick test (SPT) randomly. IDT was performed by using domestic Der p allergen fluid, and SPT was performed by using standardized Der p allergen fluid of allergopharma, histamine was positive control, normal saline was negative control, respectively. The degree of positive skin reactivity was scored as (+, ++, +++) and (++++). Then, their testing results were observed respectively and compared each other. Results There were 154 cases received IDT, another 152 cases were given SPT. IDT was positive in 88.69% of patients, SPT was positive in 90.79% of patients, there were no significant differences between them (P>0.05), but the score of the skin test was≥++ rate of group SPT was significantly higher than that of group IDT(P<0.001).All the side effects were light. Conclusionn The higher positive rate with Der p test can be determined by all the two kinds of inspiratory allergen series prepared in any ways, either as domestic Der p allergen fluid or standard Der p Allergopharma. The SPT tests are more sensitive and equally specific compared with the IDT method. |
| Key words: Allergen Allergic rhinitis Intradermal test Skin prick test |
