引用本文:闭伟文,潘其重,陆日坚.序贯疗法与传统三联疗法根治幽门螺旋杆菌感染的疗效观察[J].中国临床新医学,2015,8(5):446-448.
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序贯疗法与传统三联疗法根治幽门螺旋杆菌感染的疗效观察
闭伟文,潘其重,陆日坚
532800 广西,天等县人民医院内科
摘要:
[摘要] 目的 观察临床应用序贯疗法与传统三联疗法根治幽门螺旋杆菌(HP)的效果。方法 将2012-05~2014-05住院治疗的72例HP感染患者随机分为观察组和对照组各36例,对照组采用传统三联疗法治疗,观察组采用序贯疗法治疗,比较两组的临床疗效。结果 治疗后,观察组的HP根除率为94.44%(34/36),优于对照组的77.78%(28/36),差异有统计学意义(P<0.05);观察组不良反应率为5.56%(2/36),对照组为11.11%(4/36),两组比较差异无统计学意义(P>0.05)。结论 应用序贯疗法根治HP感染,疗效优于传统三联疗法,可选择为本地区根治HP的一线治疗方案。
关键词:  序贯疗法  传统三联疗法  幽门螺旋杆菌  疗效
DOI:10.3969/j.issn.1674-3806.2015.05.18
分类号:R 573.1
基金项目:
Analysis of the sequential therapy and the traditional triple therapy effects on helicobacter pylori infection
BI Wei-wen, PAN Qi-zhong, LU Ri-jian
Department of Internal Medicine, the People′s Hospital of Tiandeng County, Guangxi 532800, China
Abstract:
[Abstract] Objective To compare the efficacy of sequential therapy and the traditional triple therapy on helicobacter pylori(HP) infection.Methods 72 patients with HP infection from May 2012 to May 2014, were randomly divided into 2 groups, the control group and the observation group, with 36 cases in each group. The control group was performed traditional triple therapy and the observation group was performed sequential therapy. The clinical effect was compared between the two groups.Results The eradication rate of HP was 94.44%(34/36) in the observation group and 77.78%(28/36) in the control group. There was significantly difference between the two groups(P<0.05). The adverse reaction rate was 5.56%(2/36) in the observation group and 11.11%(4/36) in the control group. There was no significantly difference between the two groups(P>0.05).Conclusion Sequential therapy is more effective in the treatment of HP infection than traditional triple therapy.
Key words:  Sequential therapy  Traditional triple therapy  Helicobacter pylori(HP)  Curative effect