| 摘要: |
| ［摘要］ 目前寡转移前列腺癌的治疗以全身系统性治疗为主，针对原发灶的局部治疗缺乏高等级的研究证据。部分学者针对转移负荷小的患者提出寡转移前列腺癌的概念，认为转移灶在5个以内的前列腺癌患者预后相对较好，但各研究所纳入的寡转移标准并不统一。根据既往的数据库回顾研究，针对转移负荷小的前列腺癌患者进行原发灶的放疗或手术可以改善患者的整体预后，但仍缺乏大样本的随机对照研究证实其有效性。现对已有的寡转移前列腺癌的局部治疗研究进展进行综述，评价对寡转移前列腺癌行原发灶局部治疗的可行性和有效性。 |
| 关键词: 前列腺癌 寡转移 局部治疗 |
| DOI：10.3969/j.issn.1674-3806.2021.07.04 |
| 分类号:R 737.25 |
| 基金项目: |
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| Advances in local treatment of primary focus of oligonucleotide metastatic prostate cancer |
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HOU Hui-min, LIU Ming
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Department of Urology, Beijing Hospital, Beijing 100730, China
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| Abstract: |
| ［Abstract］ At present, systemic treatment is the main treatment for oligonucleotide metastatic prostate cancer, and there is a lack of high-level research evidence for local treatment of primary focus of metastatic prostate cancer. Some scholars put forward the concept of oligonucleotide metastatic prostate cancer for patients with small metastatic load, believing that prostate cancer patients with metastatic foci less than 5 have a relatively good prognosis. However, the criteria of oligosaccharide transfer included in various studies are not uniform. According to previous database retrospective studies, radiotherapy for primary focus of metastatic prostate cancer or surgery can improve the overall prognosis of prostate cancer patients with small metastatic load, but there is still a lack of large-sample randomized controlled studies to confirm its effectiveness. This paper reviews the existing studies on local treatment of oligonucleotide metastatic prostate cancer and evaluates the feasibility and effectiveness of local treatment of primary focus of oligonucleotide metastatic prostate cancer. |
| Key words: Prostate cancer Oligometastases Local treatment |
