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绝经管理与绝经激素治疗最新中外相关指南解读
黄菲玲,陈 蓉
中国医学科学院北京协和医学院,北京协和医院妇产科学系,妇科内分泌与生殖中心,国家妇产疾病临床研究中心,国家妇科专业医疗质量控制中心,北京 100730
摘要:
[摘要] 绝经是卵巢功能衰竭的标志性事件。卵巢功能衰竭过程中,雌激素水平的波动性下降及缺乏会导致一系列的绝经相关症状,并增加许多代谢性疾病的风险,对女性的长期健康风险及生活质量影响重大。绝经管理需在缓解绝经相关症状的同时预防远期慢性疾病。2023—2024年中华医学会妇产科学分会绝经学组、国际妇产科联盟(FIGO)、国际绝经学会(IMS)相继发布了《中国绝经管理与绝经激素治疗指南2023版》《FIGO立场声明:如何为绝经女性阐述绝经激素治疗的利弊》《IMS关于绝经和绝经激素治疗核心争议的2024白皮书》3篇关于绝经管理和绝经激素治疗的重要文献。该文就上述3篇文献的核心要点进行综合解读,以期帮助临床医师了解学科进展,更好地管理和防治绝经相关症状及疾病。
关键词:  绝经  绝经激素治疗  指南  FIGO立场声明  国际绝经学会白皮书  解读
DOI:10.3969/j.issn.1674-3806.2025.05.02
分类号:R 711.75
基金项目:北京协和医院中央高水平医院临床科研专项项目(编号:2022-PUMCH-B-123);国家临床重点专科建设项目(编号:U114000)
Interpretation of updated domestic and foreign guidelines on menopause management and menopausal hormone therapy
HUANG Feiling, CHEN Rong
Gynecological Endocrinology and Reproduction Center, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Clinical Research Center for Obstetric and Gynecologic Diseases, National Center for Healthcare Quality Management in Gynecological Diseases, Beijing 100730, China
Abstract:
[Abstract] Menopause is a landmark event of ovarian failure. During the process of ovarian failure, the fluctuating decline levels and deficiency of estrogen can lead to a series of menopausal symptoms and increase the risk of many metabolic diseases, having a significant impact on the affected women′s long-term health risks and quality of life. Menopause management needs the prevention of long-term chronic diseases while alleviating menopause-related symptoms. Between 2023 and 2024, the Menopausal Study Group of the Obstetrics and Gynecology Branch of the Chinese Medical Association, the International Federation of Gynecology and Obstetrics(FIGO), and the International Menopause Society(IMS) successively released Chinese Guidelines for Menopause Management and Menopausal Hormone Therapy, 2023 Edition, the FIGO Position Statement: How to Explain the Advantages and Disadvantages of Menopausal Hormone Therapy for Postmenopausal Women and the 2024 White Paper of the International Menopause Society on Core Disputes of Menopause and Menopausal Hormone Therapy, which are 3 papers of important literature on menopause and menopausal hormone therapy. This paper conducts a comprehensive interpretation based on the core points of the above three papers, with the aim of helping clinicians understand the progress of the discipline and better manage, prevent and treat menopause-related symptoms and diseases.
Key words:  Menopause  Menopausal hormone therapy  Guideline  FIGO position statement  International Menopause Society White Paper  Interpretation